Process Development
We transform laboratory chemical routes into scalable, robust, and cost-effective industrial processes
Our Role
We combine scientific rigor and industrial vision to design, optimize, and validate complex chemical processes. Our goal is to minimize risks during scale-up, reduce manufacturing costs, and ensure that every batch meets the highest quality standards from the very first day (right-first-time).
Synthetic Route Deve lopment and Optimization
Development of scalable and cost-efficient chemical routes.
Minimization of side reactions and impurities at the molecular level.
Laboratory-to-Plant Bridge
Pre-validation of laboratory findings to ensure success at the pilot scale.
Precise definition of Critical Process Parameters (CPPs) for robust manufacturing through Quality by Design (QbD).
Process Stabilization
Technical interventions to stabilize inconsistent process yields.
Resolution of complex industrial deviations in APIs using Root Cause Analysis (RCA).
Analytical Alignment
Optimization of complex R&D procedures for routine Quality Control (QC).
Assurance of chemical integrity from early development to commercialization.
Representative Engagements
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Scientific action: Isolated dimer trace; nitration mechanism identified. Redesigned control pH.
Result: 100% color compliance restored through a more streamlined and validated process.
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Scientific action: Aqueous feed design (Oxone/EDTA). Precise low-temperature kinetic control.
Result: "Low conversion" bottleneck resolved with a production-ready protocol.
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Scientific action: Development of an in-situ (one-pot) synthesis that eliminated the need to isolate the compound.
Result: Massive reduction in costs and lead times.
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Scientific action: Transition to a neutral pH and room-temperature protocol using an alternative chloride source compatible with stainless steel.
Result: Elimination of the need for multi-thousand-euro investments in glass-lined reactors and enhanced safety.